Carboranes in the chemist's toolbox.

@article{Grimes2015CarboranesIT,
  title={Carboranes in the chemist's toolbox.},
  author={Russell N. Grimes},
  journal={Dalton transactions},
  year={2015},
  volume={44 13},
  pages={
          5939-56
        }
}
  • R. Grimes
  • Published 17 March 2015
  • Chemistry
  • Dalton transactions
Once seldom encountered outside of a few laboratories, carboranes are now everywhere, playing a role in the development of a broad range of technologies encompassing organic synthesis, radionuclide handling, drug design, heat-resistant polymers, cancer therapy, nanomaterials, catalysis, metal-organic frameworks, molecular machines, batteries, electronic devices, and more. This perspective highlights selected examples in which the special attributes of carboranes and metallacarboranes are being… 

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References

SHOWING 1-10 OF 173 REFERENCES

Synthesis and Serendipity in Boron Chemistry: A 50 Year Perspective

Abstract Chance discovery is ubiquitous in the history of science, especially in areas where theory has tended to lag behind experimental findings. In fields such as organometallic and boron cluster

B-Mercaptocarboranes: A New Synthetic Route

Invited for the cover of this issue is the group of M. Frederick Hawthorne at the University of Missouri. The cover image shows a novel route for synthesis of 3-SH-1,2-dicarba-closo-dodecaborane

Fusing N-heterocyclic carbenes with carborane anions.

The fusion of two families of unusual carbon-containing molecules that readily disregard the tendency of carbon to form four chemical bonds, namely N-heterocyclic carbenes (NHCs) and carborane anions is described, indicating that the combination of two unusual forms of carbon atoms can lead to unexpected chemical behavior.

The use of carboranylphosphite ligands in Rh-catalyzed hydroformylation of alkenes in supercritical carbon dioxide

Novel carborane-containing phosphites were synthesized. The efficiency of the ligands was tested in the Rh-catalyzed hydroformylation of styrene, hept-1-ene, and oct-1-ene in super-critical carbon

“Click” Chemistry-Mediated Phenylene-Cored Carborane Dendrimers

The biological evaluation of branched dendrimer 16 containing nine carborane cages has been carried out using human liver cancer cells (SK-Hep1) and indicates that such dendritic boron drug delivery platforms could be possible for application in borons neutron capture therapy in cancer treatment.

Polyhedral borane derivatives: Unique and versatile structural motifs

Compounds with polyhedral borane moieties have demonstrated numerous unique properties for a variety of applications, including nanoelectronics, drug delivery vehicles, and live cell imaging.

Carborane-containing poly(fluorene): response to solvent vapors and amines.

It is reported that films of poly(fluorene) with o-carborane in the backbone function as vapochromatic photoluminescent sensors toward volatile organic molecules.

Boron chemistry lights the way: optical properties of molecular and polymeric systems.

This minireview summarizes recent work on compounds with 3- and 4-coordinate boron as well as borons clusters, placing it in the context of prior studies by the research groups of Williams and Glowgowski, Kaim, Lequan, and Marder.
...