Carboplatin and vincristine chemotherapy for children with newly diagnosed progressive low-grade gliomas.

@article{Packer1997CarboplatinAV,
  title={Carboplatin and vincristine chemotherapy for children with newly diagnosed progressive low-grade gliomas.},
  author={Roger J. Packer and Joann L. Ater and Jeffrey Allen and Peter Phillips and Russel Geyer and H. Stacy Nicholson and Regina Jakacki and Elizabeth Kurczynski and Michael N Needle and Jonathan Finlay and Gregory Reaman and James M. Boyett},
  journal={Journal of neurosurgery},
  year={1997},
  volume={86 5},
  pages={747-54}
}
The optimum treatment of nonresectable low-grade gliomas of childhood remains undecided. There has been increased interest in the use of chemotherapy for young children, but little information concerning the long-term efficacy of such treatment. Seventy-eight children with a mean age of 3 years (range 3 months-16 years) who had newly diagnosed, progressive low-grade gliomas were treated with combined carboplatin and vincristine chemotherapy. The patients were followed for a median of 30 months… CONTINUE READING
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