Carboplatin allergy and IgE regulation.

  title={Carboplatin allergy and IgE regulation.},
  author={David A. Fulcher and Paul Harnett and Anna DeFazio},
  volume={48 Suppl 1},
Methods: Genome-wide DNA methylation profiling was performed on blood mononuclear cells from volunteers who had undergone objective oral food challenges, concurrent skin-prick testing and specific IgE testing. Fifty-eight food-sensitised individuals (aged 11–15 months) were assessed, half of which were clinically reactive. Reproducibility was assessed in an additional 48 samples using methylation data from an independent population of clinical food allergy. Results: Using a supervised learning… CONTINUE READING