Carbonylated proteins are eliminated during reproduction in C. elegans.


Oxidatively damaged proteins accumulate with age in many species (Stadtman (1992) Science257, 1220-1224). This means that damage must be reset at the time of reproduction. To visualize this resetting in the roundworm Caenorhabditis elegans, a novel immunofluorescence technique that allows the detection of carbonylated proteins in situ was developed. The… (More)
DOI: 10.1111/j.1474-9726.2010.00625.x


Cite this paper

@article{Goudeau2010CarbonylatedPA, title={Carbonylated proteins are eliminated during reproduction in C. elegans.}, author={J{\'e}r{\^o}me Goudeau and Hugo Aguilaniu}, journal={Aging cell}, year={2010}, volume={9 6}, pages={991-1003} }