Carbonyl reductase as a significant predictor of survival and lymph node metastasis in epithelial ovarian cancer

@article{Umemoto2001CarbonylRA,
  title={Carbonyl reductase as a significant predictor of survival and lymph node metastasis in epithelial ovarian cancer},
  author={Masahiko Umemoto and Yoshihito Yokoyama and Suguru Sato and Shigeki Tsuchida and Fahd R Al-Mulla and Yoshiaki Saito},
  journal={British Journal of Cancer},
  year={2001},
  volume={85},
  pages={1032 - 1036}
}
We have recently reported a novel function for carbonyl reductase (CR), namely, its ability to modulate the metastatic potential of malignant mouse cells. Because there are currently no data addressing a similar function for CR in human cancers, the aim of this study was to assess a correlation between survival and metastasis, and CR level in epithelial ovarian cancer. Using anti-CR antibody, immunohistochemical staining was performed on 73 epithelial ovarian cancers, 13 borderline malignant… CONTINUE READING