Carbonyl levels in type I and II fiber-rich muscles and their response to chronic ethanol feeding in vivo and hydroxyl and superoxide radicals in vitro.

@article{KooNg2000CarbonylLI,
  title={Carbonyl levels in type I and II fiber-rich muscles and their response to chronic ethanol feeding in vivo and hydroxyl and superoxide radicals in vitro.},
  author={R Koo-Ng and G Falkous and Mike Reilly and Timothy J. Peters and David Mantle and Victor R. Preedy},
  journal={Alcoholism, clinical and experimental research},
  year={2000},
  volume={24 12},
  pages={1862-8}
}
BACKGROUND Chronic alcoholic myopathy is characterized by selective reductions in the size of Type II skeletal muscle fibers (i.e., glycolytic, anaerobic fast-twitch). Type I (i.e., oxidative, aerobic, slow twitch) fibers are relatively resistant. It is possible that reactive oxygen species may preferentially damage the Type II fibers because the concentrations of several antioxidant enzymes are lower in Type II compared with Type I fibers. METHODS To test the hypothesis, we measured protein… CONTINUE READING

From This Paper

Figures, tables, results, connections, and topics extracted from this paper.
4 Extracted Citations
0 Extracted References
Similar Papers