Carbonyl Scavenging as an Antioxidant Neuroprotective Strategy for Acute Traumatic Brain Injury

@inproceedings{Cebak2017CarbonylSA,
  title={Carbonyl Scavenging as an Antioxidant Neuroprotective Strategy for Acute Traumatic Brain Injury},
  author={John E. Cebak and Indrapal N. Singh and Juan Wang and Rachel L. Hill and Jacqueline R. Kulbe and Edward D. Hall},
  year={2017}
}
Abstract Reactive oxygen-induced lipid peroxidation (LP) has been documented to play a critical role in pathophysiology, neurodegeneration, and neurological disability that follows acute traumatic brain injury (TBI) and spinal cord injury (SCI). Consistent with that fact, a number of antioxidant compounds that either scavenges reactive oxygen species or directly inhibit LP have been shown to be protective in preclinical models of TBI and SCI. Although LP is able to damage neural cellular and… CONTINUE READING

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