Carbonic anhydrase inhibitors and ventilation: a complex interplay of stimulation and suppression.

@article{Swenson1998CarbonicAI,
  title={Carbonic anhydrase inhibitors and ventilation: a complex interplay of stimulation and suppression.},
  author={Erik R Swenson},
  journal={The European respiratory journal},
  year={1998},
  volume={12 6},
  pages={
          1242-7
        }
}
Inhibitors of carbonic anhydrase (CA) have long been used as respiratory stimulants, most successfully in acute mountain sickness (AMS), but also in chronic obstructive pulmonary disease (COPD) and sleep-disordered breathing syndromes. Although effective, presently available inhibitors have minor annoying side-effects (paraesthesias, mild nausea and gastrointestinal discomfort) that can limit long-term compliance; and in certain cases their use may be hazardous, particularly in those with… CONTINUE READING
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