Carbonic anhydrase IX expression in renal neoplasms: correlation with tumor type and grade.

@article{Genega2010CarbonicAI,
  title={Carbonic anhydrase IX expression in renal neoplasms: correlation with tumor type and grade.},
  author={Elizabeth M. Genega and Musie S. Ghebremichael and R. Najarian and Yineng Fu and Yihong Wang and Pedram Argani and Chiara Grisanzio and Sabina Signoretti},
  journal={American journal of clinical pathology},
  year={2010},
  volume={134 6},
  pages={873-9}
}
Carbonic anhydrase IX (CAIX), a hypoxia-induced protein, is expressed in some renal tumors. We evaluated its immunohistochemical expression in 317 primary and 42 metastatic renal neoplasms (186 clear cell, 52 papillary, 35 chromophobe, 47 unclassified, and 15 Xp11.2 translocation renal cell carcinomas [RCCs]; 26 oncocytomas; 2 metanephric adenomas; 1 urothelial carcinoma; 1 mixed epithelial and stromal tumor; and 1 angiomyolipoma); 7 neoplasms were unknown as to whether they were primary or… CONTINUE READING