Carbon nanotubes as intracellular protein transporters: generality and biological functionality.

@article{Kam2005CarbonNA,
  title={Carbon nanotubes as intracellular protein transporters: generality and biological functionality.},
  author={Nadine Wong Shi Kam and Hongjie Dai},
  journal={Journal of the American Chemical Society},
  year={2005},
  volume={127 16},
  pages={6021-6}
}
Various proteins adsorb spontaneously on the sidewalls of acid-oxidized single-walled carbon nanotubes. This simple nonspecific binding scheme can be used to afford noncovalent protein-nanotube conjugates. The proteins are found to be readily transported inside various mammalian cells with nanotubes acting as the transporter via the endocytosis pathway. Once released from the endosomes, the internalized protein-nanotube conjugates can enter into the cytoplasm of cells and perform biological… CONTINUE READING