Carbon monoxide exchanges between the human fetus and mother: a mathematical model.

@article{Hill1977CarbonME,
  title={Carbon monoxide exchanges between the human fetus and mother: a mathematical model.},
  author={Esther P. Hill and Jeffrey R. Hill and Gordon Power and Lawrence D. Longo},
  journal={The American journal of physiology},
  year={1977},
  volume={232 3},
  pages={H311-23}
}
A mathematical model was developed to calculate maternal and fetal carboxyhemoglobin concentrations, [HbCO], as functions of time during and after exposure of the mother to various inspired CO concentrations. Effects of variation in alveolar ventilation rates, pulmonary and placental fiffusing capacities, cardiac output, endogenous carbon monoxide production and other factors were studied. Following a change in the inspired CO concentration, fetal HbCO lags behind maternal HbCO by several hours… CONTINUE READING