Carbon monoxide can prevent acute lung injury observed after ischemia reperfusion of the lower extremities.

@article{Boutros2007CarbonMC,
  title={Carbon monoxide can prevent acute lung injury observed after ischemia reperfusion of the lower extremities.},
  author={Cherif N Boutros and Rachid Zegdi and Nermine Lila and Mich{\`e}le Cambillau and Paul Forn{\'e}s and Alain Carpentier and Jean Noel Fabini},
  journal={The Journal of surgical research},
  year={2007},
  volume={143 2},
  pages={437-42}
}
BACKGROUND Pulmonary expression of heme oxygenase has been observed in multiple studies. This expression has been found beneficial in decreasing the severity of acute lung injury (ALI) post ischemia-reperfusion (I/R). The aim of this study was to assess the role of exogenous administration of the end-products of heme oxygenase reaction, carbon monoxide, and bilirubin, in the severity of ALI. STUDY DESIGN We compared five groups of rats (n = 7/group) including a sham group and four I/R of the… CONTINUE READING