Carbon metabolism of intracellular bacterial pathogens and possible links to virulence

  title={Carbon metabolism of intracellular bacterial pathogens and possible links to virulence},
  author={Wolfgang Eisenreich and Thomas Dandekar and Juergen Heesemann and W. Goebel},
  journal={Nature Reviews Microbiology},
New technologies such as high-throughput methods and 13C-isotopologue-profiling analysis are beginning to provide us with insight into the in vivo metabolism of microorganisms, especially in the host cell compartments that are colonized by intracellular bacterial pathogens. In this Review, we discuss the recent progress made in determining the major carbon sources and metabolic pathways used by model intracellular bacterial pathogens that replicate either in the cytosol or in vacuoles of… CONTINUE READING

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