Carbon ions-induced apoptosis in hematopoietic tumor cell lines.


BACKGROUND The purpose of this study was to assess apoptosis in hematopoietic tumor cells irradiated with carbon ions, in order to define its contribution to the cytotoxicity of these high-LET radiations. MATERIALS AND METHODS RDM4 (murine T lymphoma), MOLT-4, TK6 and WTK1 (human lymphoblastoid) cells were irradiated with 12C or 13C. Apoptosis was… (More)


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