Carbon-fate maps for metabolic reactions
@article{Mu2007CarbonfateMF,
title={Carbon-fate maps for metabolic reactions},
author={Fangping Mu and Robert F. Williams and Clifford J. Unkefer and Pat J. Unkefer and James R. Faeder and William S. Hlavacek},
journal={Bioinformatics},
year={2007},
volume={23 23},
pages={
3193-9
}
}MOTIVATION
Stable isotope labeling of small-molecule metabolites (e.g. (13)C-labeling of glucose) is a powerful tool for characterizing pathways and reaction fluxes in a metabolic network. Analysis of isotope labeling patterns requires knowledge of the fates of individual atoms and moieties in reactions, which can be difficult to collect in a useful form when considering a large number of enzymatic reactions.
RESULTS
We report carbon-fate maps for 4605 enzyme-catalyzed reactions documented in…
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