Carbon dioxide differentially affects the cytokine release of macrophage subpopulations exclusively via alteration of extracellular pH

@article{Kos2004CarbonDD,
  title={Carbon dioxide differentially affects the cytokine release of macrophage subpopulations exclusively via alteration of extracellular pH},
  author={Marcin Kos and Joachim Friedrich Kuebler and Natalie K. Jesch and Gertrud Vieten and Nikolaas M. A. Bax and David C. van der Zee and Roger Busche and Benno Manfred Ure},
  journal={Surgical Endoscopy And Other Interventional Techniques},
  year={2004},
  volume={20},
  pages={570-576}
}
The improved outcome after endoscopic surgery has been attributed to less surgical trauma. However, the underlying mechanisms are not fully understood, and direct effects of CO2 used for pneumoperitoneum, cellular acidification, and/or the lack of air contamination have been postulated to additionally modulate immune functions during endoscopic surgery. We investigated the effects of CO2 incubation, extracellular acidification, and air contamination on the inflammatory response of two distinct… CONTINUE READING

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Expansion beyond compression

  • MP Gallery
  • Surg Endosc
  • 2003

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