Carbon catabolite repression in bacteria: many ways to make the most out of nutrients

  title={Carbon catabolite repression in bacteria: many ways to make the most out of nutrients},
  author={B. G{\"o}rke and J. St{\"u}lke},
  journal={Nature Reviews Microbiology},
  • B. Görke, J. Stülke
  • Published 2008
  • Biology, Medicine
  • Nature Reviews Microbiology
  • Most bacteria can selectively use substrates from a mixture of different carbon sources. The presence of preferred carbon sources prevents the expression, and often also the activity, of catabolic systems that enable the use of secondary substrates. This regulation, called carbon catabolite repression (CCR), can be achieved by different regulatory mechanisms, including transcription activation and repression and control of translation by an RNA-binding protein, in different bacteria. Moreover… CONTINUE READING
    1,111 Citations

    Figures and Topics from this paper

    La répression catabolique ou comment les bactéries choisissent leurs sucres préférés
    • 1
    • PDF
    The role of protein phosphorylation in regulation of carbon catabolite repression in Bacillus subtilis
    • Highly Influenced
    Carbon catabolite regulation in Streptomyces: new insights and lessons learned
    • 12


    Carbon catabolite repression in bacteria.
    • 433
    The mechanisms of carbon catabolite repression in bacteria.
    • J. Deutscher
    • Biology, Medicine
    • Current opinion in microbiology
    • 2008
    • 488
    CcpA-Dependent Carbon Catabolite Repression in Bacteria
    • 229
    • PDF
    Bacterial phosphotransferase system (PTS) in carbohydrate uptake and control of carbon metabolism.
    • 141