Carbon catabolite repression in bacteria: many ways to make the most out of nutrients

@article{Grke2008CarbonCR,
  title={Carbon catabolite repression in bacteria: many ways to make the most out of nutrients},
  author={Boris G{\"o}rke and J{\"o}rg St{\"u}lke},
  journal={Nature Reviews Microbiology},
  year={2008},
  volume={6},
  pages={613-624}
}
Most bacteria can selectively use substrates from a mixture of different carbon sources. The presence of preferred carbon sources prevents the expression, and often also the activity, of catabolic systems that enable the use of secondary substrates. This regulation, called carbon catabolite repression (CCR), can be achieved by different regulatory mechanisms, including transcription activation and repression and control of translation by an RNA-binding protein, in different bacteria. Moreover… 
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