Carbon Monoxide-Releasing Molecules: Characterization of Biochemical and Vascular Activities

@article{Motterlini2002CarbonMM,
  title={Carbon Monoxide-Releasing Molecules: Characterization of Biochemical and Vascular Activities},
  author={R. Motterlini and James E. Clark and R. Foresti and P. Sarathchandra and B. Mann and C. Green},
  journal={Circulation Research: Journal of the American Heart Association},
  year={2002},
  volume={90},
  pages={e17-e24}
}
Carbon monoxide (CO) is generated in living organisms during the degradation of heme by the enzyme heme oxygenase, which exists in constitutive (HO-2 and HO-3) and inducible (HO-1) isoforms. Carbon monoxide gas is known to dilate blood vessels in a manner similar to nitric oxide and has been recently shown to possess antiinflammatory and antiapoptotic properties. We report that a series of transition metal carbonyls, termed here carbon monoxide-releasing molecules (CO-RMs), liberate CO to… Expand
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5
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References

SHOWING 1-10 OF 38 REFERENCES
Carbon monoxide: an endogenous modulator of sinusoidal tone in the perfused rat liver.
The heme oxygenase system: a regulator of second messenger gases.
  • M. Maines
  • Chemistry, Medicine
  • Annual review of pharmacology and toxicology
  • 1997
Carbon Monoxide Generated by Heme Oxygenase 1 Suppresses Endothelial Cell Apoptosis
Carbon monoxide provides protection against hyperoxic lung injury.
Endothelial Heme Oxygenase-1 Induction by Hypoxia
...
1
2
3
4
...