Carbon Monoxide Pollution Impairs Myocardial Perfusion Reserve: Implication of Coronary Endothelial Dysfunction

@article{Meyer2011CarbonMP,
  title={Carbon Monoxide Pollution Impairs Myocardial Perfusion Reserve: Implication of Coronary Endothelial Dysfunction},
  author={Gr{\'e}gory Meyer and Julien Boissi{\`e}re and Stephane Tanguy and Caroline Rugale and Sandrine Gayrard and Bernard Jover and Philippe Obert and Cyril F. Reboul},
  journal={Cardiovascular Toxicology},
  year={2011},
  volume={11},
  pages={334-340}
}
Chronic exposure to simulated urban CO pollution is reported to be associated with cardiac dysfunction. Despite the potential implication of myocardial perfusion alteration in the pathophysiology of CO pollution, the underlying mechanisms remain today still unknown. Therefore, the aim of this work was to evaluate the effects of prolonged exposure to simulated urban CO pollution on the regulation of myocardial perfusion. Cardiac hemodynamics and myocardial perfusion were assessed under basal… CONTINUE READING
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