Carbon Monoxide Dehydrogenases.
@article{Jeoung2019CarbonMD, title={Carbon Monoxide Dehydrogenases.}, author={Jae‐Hun Jeoung and Berta M. Martins and Holger Dobbek}, journal={Methods in molecular biology}, year={2019}, volume={1876}, pages={ 37-54 } }
Carbon monoxide dehydrogenases (CODHs) catalyze the reversible oxidation of CO with water to CO2, two electrons, and two protons. Two classes of CODHs exist, having evolved from different scaffolds featuring active sites built from different transition metals. The basic properties of both classes are described in this overview chapter.
5 Citations
Anaerobic carboxydotrophy in sulfur-respiring haloarchaea from hypersaline lakes.
- BiologyThe ISME journal
- 2022
Overall, this work demonstrated for the first time the potential for anaerobic sulfur-dependent carboxydotrophy in extremely halophilic archaea.
CO2-Fixation Strategies in Energy Extremophiles: What Can We Learn From Acetogens?
- Biology, EngineeringFrontiers in Microbiology
- 2020
This mini-review summarizes the current knowledge gathered on the CO2-fixation strategies among acetogens and applies the structural information obtained from hydrogenotrophic methanogens to highlight common features, as well as the specific differences of their CO2 -fixation systems.
Physiological Effects of 2-Bromoethanesulfonate on Hydrogenotrophic Pure and Mixed Cultures
- BiologyMicroorganisms
- 2022
Results indicate that formate is an important intermediate of hydrogenotrophic metabolism accumulating upon methanogenesis inhibition, and this work aims to investigate competing reactions like homoacetogenesis in mixed cultures.
A Brief History of Carbon Monoxide and Its Therapeutic Origins.
- Environmental ScienceNitric oxide : biology and chemistry
- 2021
References
SHOWING 1-10 OF 74 REFERENCES
The aerobic CO dehydrogenase from Oligotropha carboxidovorans
- ChemistryJBIC Journal of Biological Inorganic Chemistry
- 2014
AbstractWe review here the recent literature
dealing with the molybdenum- and copper-dependent CO dehydrogenase, with particular emphasis on the structure of the enzyme and recent advances in our…
A new pathway of autotrophic growth utilizing carbon monoxide or carbon dioxide and hydrogen.
- Chemistry, BiologyBiochemistry international
- 1986
The discovery of a pathway of autotrophic growth is described in which carbon monoxide or carbon dioxide and hydrogen is used as the source of carbon and energy. Carbon monoxide dehydrogenase is the…
The Carbon Monoxide Dehydrogenase from Desulfovibrio vulgaris.
- BiologyBiochimica et biophysica acta
- 2015
Carbon Monoxide Dehydrogenase Reduces Cyanate to Cyanide.
- Chemistry, BiologyAngewandte Chemie
- 2017
First evidences for a cyanate to cyanide reduction at the C-cluster are reported, which could mimic CO2 turnover and open new perspectives for elucidation of the detailed catalytic mechanism of CODH.
The Ni-containing carbon monoxide dehydrogenase family: light at the end of the tunnel?
- Chemistry
- 2002
OAK-B135 Metalloenzymes seem to ''come of age'' when their structures are known at atomic resolution, spectroscopic and catalytic properties are basically understood, and genetic expression systems…
Carbon monoxide dehydrogenase reaction mechanism: a likely case of abnormal CO2 insertion to a Ni-H(-) bond.
- ChemistryInorganic chemistry
- 2011
A revised version of an earlier proposal for the catalytic cycle of Ni-containing CODH that agrees with available spectroscopic and structural data is put forward.
Rapid and efficient electrocatalytic CO2/CO interconversions by Carboxydothermus hydrogenoformans CO dehydrogenase I on an electrode.
- ChemistryJournal of the American Chemical Society
- 2007
The Ni-containing carbon monoxide dehydrogenase I from Carboxydothermus hydrogenoformans adsorbed on a pyrolytic graphite “edge” electrode catalyzes rapid CO2/CO interconversions at the thermodynamic…
Orbital contributions to CO oxidation in Mo-Cu carbon monoxide dehydrogenase.
- Chemistry, PhysicsChemical communications
- 2014
A molecular orbital analysis provides new insight into the mechanism of Mo/Cu carbon monoxide dehydrogenase, and reveals electronic structure contributions to reactivity that are remarkably similar…
Structural basis of cyanide inhibition of Ni, Fe-containing carbon monoxide dehydrogenase.
- Chemistry, BiologyJournal of the American Chemical Society
- 2009
The crystal structure of CODH-II from Carboxydothermus hydrogenoformans in complex with cyanide is reported and it is suggested that the competitive inhibitory character of cyanide originates from it obstruction of carbon monoxide binding to the nickel ion while the slow binding inhibition is due to a conformational change of the protein during which the water/hydroxo-ligand bound to iron is lost.
Reaction of the molybdenum- and copper-containing carbon monoxide dehydrogenase from Oligotropha carboxydovorans with quinones.
- Chemistry, BiologyBiochemistry
- 2011
The results strongly suggest that CODH donates reducing equivalents directly to the quinone pool without using a cytochrome as an intermediary.