Corpus ID: 54954091

Carboline Alkaloid – Enriched Extract from the Amazonian Rain Forest Tree Pao Pereira Suppresses Prostate Cancer Cells

  title={Carboline Alkaloid – Enriched Extract from the Amazonian Rain Forest Tree Pao Pereira Suppresses Prostate Cancer Cells},
  author={Debra Bemis and Jillian L. Capodice and Manisha Desai and Aaron E. Katz and Ralph Buttyan},
Journal of the Society for Integrative Oncology, Vol 7, No 2 (Spring), 2009: pp 59–65 59 © 2009 BC Decker Inc bark extract is enriched for alkaloids of the -carboline family. These types of alkaloids have been shown to be cytotoxic for cancer cells, and their mechanism of action may involve the targeting of cyclin-dependent kinases (CDKs). None of the previous studies on pao pereira bark extracts involved human prostate cancer cell lines, so here we report our preclinical studies to test… Expand

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