Carbohydrate specificity of sea urchin sperm bindin: a cell surface lectin mediating sperm-egg adhesion

  title={Carbohydrate specificity of sea urchin sperm bindin: a cell surface lectin mediating sperm-egg adhesion},
  author={Charles G. Glabe and Laura B. Grabel and Victor D. Vacquier and S D Rosen},
  journal={The Journal of Cell Biology},
  pages={123 - 128}
We have examined the carbohydrate specificity of bindin, a sperm protein responsible for the adhesion of sea urchin sperm to eggs, by investigating the interaction of a number of polysaccharides and glycoconjugates with isolated bindin. Several of these polysaccharides inhibit the agglutination of eggs by bindin particles. An egg surface polysaccharide was found to be the most potent inhibitor of bindin-mediated egg agglutination. Fucoidin, a sulfated fucose heteropolysaccharide, was the next… CONTINUE READING


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