Carbohydrate-functionalized collagen matrices: design and characterization of a novel neoglycosylated biomaterial.

@article{Russo2014CarbohydratefunctionalizedCM,
  title={Carbohydrate-functionalized collagen matrices: design and characterization of a novel neoglycosylated biomaterial.},
  author={Laura Russo and Alfonso Gautieri and Mario Raspanti and Francesca Taraballi and Francesco Nicotra and Simone Vesentini and Laura Cipolla},
  journal={Carbohydrate research},
  year={2014},
  volume={389},
  pages={12-7}
}
Collagen matrices have been neoglycosylated with lactose by reductive amination at lysine side chains. AFM analysis highlights that the chemical does not affect molecular assembly into fibrils. Moreover, ELLA biochemical assays show that the glycan moiety is efficiently exposed on the matrix surface for receptor recognition.