Carbohydrate-based immune adjuvants.

  title={Carbohydrate-based immune adjuvants.},
  author={Nikolai Petrovsky and Peter D Cooper},
  journal={Expert review of vaccines},
  volume={10 4},
The role for adjuvants in human vaccines has been a matter of vigorous scientific debate, with the field hindered by the fact that for over 80 years, aluminum salts were the only adjuvants approved for human use. To this day, alum-based adjuvants, alone or combined with additional immune activators, remain the only adjuvants approved for use in the USA. This situation has not been helped by the fact that the mechanism of action of most adjuvants has been poorly understood. A relative lack of… CONTINUE READING