Carbohydrate Restriction has a More Favorable Impact on the Metabolic Syndrome than a Low Fat Diet

@article{Volek2008CarbohydrateRH,
  title={Carbohydrate Restriction has a More Favorable Impact on the Metabolic Syndrome than a Low Fat Diet},
  author={Jeff S Volek and Stephen D. Phinney and Cassandra E. Forsythe and Erin Elizabeth Quann and Richard James Wood and Michael Joseph Puglisi and William J. Kraemer and Douglas M. Bibus and Maria Luz Fern{\'a}ndez and Richard D. Feinman},
  journal={Lipids},
  year={2008},
  volume={44},
  pages={297-309}
}
We recently proposed that the biological markers improved by carbohydrate restriction were precisely those that define the metabolic syndrome (MetS), and that the common thread was regulation of insulin as a control element. We specifically tested the idea with a 12-week study comparing two hypocaloric diets (~1,500 kcal): a carbohydrate-restricted diet (CRD) (%carbohydrate:fat:protein = 12:59:28) and a low-fat diet (LFD) (56:24:20) in 40 subjects with atherogenic dyslipidemia. Both… 

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TLDR
It is felt that MetS is a meaningful, useful phenomenon and may, in fact, be operationally defined as the set of markers that responds to CHO restriction, and may provide a new experimental criterion for MetS in the face of on-going controversy about a useful definition.

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It seems appropriate to consider carbohydrate reduction as a useful, if not the preferred, alternative to low-fat diets, which have met with limited success.

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