Carbofuran-induced oxidative stress in mammalian brain.

  title={Carbofuran-induced oxidative stress in mammalian brain.},
  author={Devendra Kumar Rai and B. Lungsi Sharma},
  journal={Molecular biotechnology},
  volume={37 1},
Chronic exposure to carbofuran, a carbamate pesticide, via oral administration has been reported to generate reactive oxygen species (ROS) in rat brain. However, information regarding the effect of short-term intraperitoneal (i.p.) carbofuran intoxication on oxidative stress is lacking. In the present study, the effect of carbofuran on oxidative indices in brain of Wistar rats has been determined by exposing the animals to three subacute concentrations (0.2, 0.4 and 0.8 mg/kg body weight… CONTINUE READING