Carboetomidate inhibits alpha4/beta2 neuronal nicotinic acetylcholine receptors at concentrations affecting animals.

@article{Pierce2012CarboetomidateIA,
  title={Carboetomidate inhibits alpha4/beta2 neuronal nicotinic acetylcholine receptors at concentrations affecting animals.},
  author={David W. Pierce and Ervin Pejo and Douglas E. Raines and Stuart A. Forman},
  journal={Anesthesia and analgesia},
  year={2012},
  volume={115 1},
  pages={70-2}
}
BACKGROUND Carboetomidate is an etomidate derivative that produces hypnosis without inhibiting adrenal corticosteroid synthesis. Similar to etomidate, carboetomidate modulates γ-aminobutyric acid type A receptors, but its effects on other ion channel targets of general anesthetics are unknown. METHODS We compared etomidate and carboetomidate effects on… CONTINUE READING