Carbocisteine inhibits rhinovirus infection in human tracheal epithelial cells.

  title={Carbocisteine inhibits rhinovirus infection in human tracheal epithelial cells.},
  author={Hiroyasu Yasuda and Mutsuo Yamaya and Takahiko Sasaki and D Inoue and Katsutoshi Nakayama and Mitsuhiro Yamada and Masanori Asada and Mari Yoshida and Takashi Suzuki and Hidekazu Nishimura and Hidetada Sasaki},
  journal={The European respiratory journal},
  volume={28 1},
The aim of the study was to examine the effects of a mucolytic drug, carbocisteine, on rhinovirus (RV) infection in the airways. Human tracheal epithelial cells were infected with a major-group RV, RV14. RV14 infection increased virus titres and the cytokine content of supernatants. Carbocisteine reduced supernatant virus titres, the amount of RV14 RNA in cells, cell susceptibility to RV infection and supernatant cytokine concentrations, including interleukin (IL)-6 and IL-8, after RV14… CONTINUE READING
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