Carbidopa/levodopa and selegiline do not affect platelet mitochondrial function in early parkinsonism.

Abstract

Previous studies have demonstrated impaired complex I activity in platelets from Parkinson's disease (PD) patients who were receiving levodopa and other medications for their disease. Eleven patients with early PD underwent three sequential plateletphereses: while on no medication, after receiving carbidopa/levodopa for 1 month, and after receiving… (More)

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