Carbetocin in comparison with oxytocin in several dosing regimens for the prevention of uterine atony after elective caesarean section in the Netherlands

@article{Holleboom2012CarbetocinIC,
  title={Carbetocin in comparison with oxytocin in several dosing regimens for the prevention of uterine atony after elective caesarean section in the Netherlands},
  author={C. A. G. Holleboom and Jim van Eyck and Steven V. Koenen and I A M Kreuwel and Fred Bergwerff and Eva Creutzberg and Hein W. Bruinse},
  journal={Archives of Gynecology and Obstetrics},
  year={2012},
  volume={287},
  pages={1111 - 1117}
}
PurposeThe aim of the study was to compare the prophylactic effects of carbetocin with those of oxytocin for the prevention of uterine atony in patients undergoing elective caesarean section (CS) in the Netherlands. The primary endpoint was the need for additional uterotonic medication.MethodsEach of the five participating Dutch hospitals treated 50–100 term patients with 100 μg of intravenous carbetocin on prescription. Each centre retrieved charts of 250 patients treated with oxytocin… Expand
Carbetocin Versus Oxytocin for Prophylaxis of PPH Used During Caesarean Section: An Open Label Randomized Control Trial
TLDR
Carbetocin appears to be an effective new drug than Oxytocin for the prevention of postpartum hemorrhage following caesarean section. Expand
Efficacy and Safety of Carbetocin in Comparison to Oxytocin for the Prevention of Primary PPH during Caesarean Section: An Open Label Randomized Control Trial
TLDR
Cbetocin appears to be an effective new drug than oxytocin for the prevention of primary postpartum hemorrhage in caesarean section, and no patient was required additional uterotonics. Expand
Comparative Study between Carbetocin versus Oxytocin in Prevention of Post-Partum Haemorrhage Following Caesarean Section in High-Risk Pregnancies
Aim of Work: To compare the effectiveness of carbetocin and oxytocin when they are administered at caesarean section for the routine prevention of postpartum hemorrhage in patients with high riskExpand
COMPARATIVE STUDY BETWEEN CARBETOCIN VERSUS OXYTOCIN FOR THE PREVENTION OF ATONIC POSTPARTUM HEMORRHAGE AFTER REPEATED ELECTIVE CESAREAN SECTIONS
Background: Postpartum hemorrhage (PPH) is a serious condition remaining the single main cause of maternal morbidity and mortality. Objective: To compare the prophylactic effects of carbetocin withExpand
[Comparison of carbetocin and oxytocin effectiveness for prevention of postpartum hemorrhage after caesarean delivery].
TLDR
Carbetocin is more effective than oxytocin in the prevention of PPH and significantly reduces the necessity to administer therapeutic uterotonics during caesarean delivery. Expand
Carbetocin versus oxytocin following vaginal and Cesarean delivery: a before-after study
TLDR
There was no difference in the use of additional uterotonics when carbetocin or oxytocin were used in a cohort of women undergoing vaginal deliveries and both elective and emergency Cesarean deliveries, and the need for blood transfusion. Expand
[Carbetocin versus Oxytocin during caesarean section for preventing postpartum haemorrhage].
TLDR
Carbetocin seems to reduce the need for postoperative intravenous iron injection, as well as the use of complementary therapies for postpartum haemorrhage, according to the primary outcome. Expand
Adverse Effects of Carbetocin versus Oxytocin in the Prevention of Postpartum Haemorrhage after Caesarean Section: A Randomized Controlled Trial
TLDR
In planned CS, a possible clinical significant lower incidence of nausea after carbetocin was noted but this was not statistically significant and there were no differences regarding BP, heart rate, the need for vasopressor, and blood loss. Expand
Efficacy and Safety of Carbetocin for the Prevention of Primary PPH During Caesarean Section: An Open Label Single Arm Study
TLDR
Cbetocin appears to be an effective new drug for the prophylaxis of postpartum hemorrhage in cesarean section, thus avoiding severe blood loss and reducing maternal morbidity and mortality. Expand
Efficacy and Safety of Carbetocin in Comparison to Oxytocin in the Active Management of Third Stage of Labour Following Vaginal Delivery: An Open Label Randomized Control Trial
TLDR
A single dose of 100 microgram IV carbetocin is more effective than oxytocin for maintaining adequate uterine tone, less blood loss and preventing postpartum bleeding in women undergoing vaginal delivery. Expand
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