Carbamylated hemoglobin: a potential marker for the adequacy of hemodialysis therapy in end-stage renal failure.

@article{Davenport1996CarbamylatedHA,
  title={Carbamylated hemoglobin: a potential marker for the adequacy of hemodialysis therapy in end-stage renal failure.},
  author={Andrew Davenport and Simon R. Jones and Sharad Goel and Jeremy Astley and Terry G Feest},
  journal={Kidney international},
  year={1996},
  volume={50 4},
  pages={1344-51}
}
Urea can dissociate in vivo to form isocyanic acid which can react with hemoglobin to form carbamylated hemoglobin. Previous work has shown that formation of carbamylated hemoglobin depends upon both the severity and the duration of renal failure. To determine whether carbamylated hemoglobin can be used as an assessment of the adequacy of hemodialysis treatment, we prospectively studied 55 stable patients who regularly attended our hospital dialysis program. Carbamylated hemoglobin was greater… CONTINUE READING