Capturing metabolite channeling in metabolic flux phenotypes.

@article{Williams2011CapturingMC,
  title={Capturing metabolite channeling in metabolic flux phenotypes.},
  author={Thomas Christopher Rhys Williams and Lee J Sweetlove and R. George Ratcliffe},
  journal={Plant physiology},
  year={2011},
  volume={157 3},
  pages={
          981-4
        }
}
Metabolite channeling, also known as substrate channeling, the process by which intermediates in metabolic pathways are passed from enzyme to enzyme without equilibration with the cellular medium, is thought to be important in the organization and regulation of metabolism (Agius and Sherratt, 1997). The process is difficult to study noninvasively, particularly in the highly connected network of central metabolism, but since channeling can provide alternative pathways its occurrence may leave a… CONTINUE READING
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