Capturing epidermal stemness for regenerative medicine.

@article{Barrandon2012CapturingES,
  title={Capturing epidermal stemness for regenerative medicine.},
  author={Yann Barrandon and Nicolas Grasset and Andrea Zaffalon and François Gorostidi and St{\'e}phanie Claudinot and St{\'e}phanie Lathion Droz-Georget and Daisuke Nanba and Ariane Rochat},
  journal={Seminars in cell & developmental biology},
  year={2012},
  volume={23 8},
  pages={937-44}
}
The skin is privileged because several skin-derived stem cells (epithelial stem cells from epidermis and its appendages, mesenchymal stem cells from dermis and subcutis, melanocyte stem cells) can be efficiently captured for therapeutic use. Main indications remain the permanent coverage of extensive third degree burns and healing of chronic cutaneous wounds, but recent advances in gene therapy technology open the door to the treatment of disabling inherited skin diseases with genetically… CONTINUE READING
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