Capturing and profiling adult hair follicle stem cells

  title={Capturing and profiling adult hair follicle stem cells},
  author={Rebecca J. Morris and Yaping Liu and Lee K Marles and Zaixin Yang and Carol S. Trempus and Shulan Li and Jamie S Lin and Janet A. Sawicki and George Cotsarelis},
  journal={Nature Biotechnology},
The hair follicle bulge possesses putative epithelial stem cells. Characterization of these cells has been hampered by the inability to target bulge cells genetically. Here, we use a Keratin1-15 (Krt1-15, also known as K15) promoter to target mouse bulge cells with an inducible Cre recombinase construct or with the gene encoding enhanced green fluorescent… CONTINUE READING