Capture of heat-killed Mycobacterium bovis bacillus Calmette-Guérin by intelectin-1 deposited on cell surfaces.

@article{Tsuji2009CaptureOH,
  title={Capture of heat-killed Mycobacterium bovis bacillus Calmette-Gu{\'e}rin by intelectin-1 deposited on cell surfaces.},
  author={Shoutaro Tsuji and Makiko Yamashita and Donald R. Hoffman and Akihito Nishiyama and Tsutomu Shinohara and Takashi Ohtsu and Yoshimi Shibata},
  journal={Glycobiology},
  year={2009},
  volume={19 5},
  pages={518-26}
}
Intelectin is an extracellular animal lectin found in chordata. Although human and mouse intelectin-1 recognize galactofuranosyl residues included in cell walls of various microorganisms, the physiological function of mammalian intelectin had been unclear. In this study, we found that human intelectin-1 was a serum protein and bound to Mycobacterium bovis bacillus Calmette-Guérin (BCG). Human intelectin-1-binding to BCG was inhibited by Ca(2+)-depletion, galactofuranosyl disaccharide, ribose… CONTINUE READING

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