Capture and visualization of live Mycobacterium tuberculosis bacilli from tuberculosis bioaerosols

@article{Dinkele2019CaptureAV,
  title={Capture and visualization of live Mycobacterium tuberculosis bacilli from tuberculosis bioaerosols},
  author={Ryan Dinkele and Sophia Gessner and A. Koch and Carl Morrow and Melitta Gqada and Mireille Kamariza and Carolyn R. Bertozzi and Brian Smith and Courtney McLoud and Andrew Evan Kamholz and Wayne Bryden and Charles J. Call and Valerie Mizrahi and Robin Wood and Digby F. Warner},
  journal={bioRxiv},
  year={2019}
}
The tuberculosis (TB) pandemic demands urgent interventions such as those designed to interrupt Mycobacterium tuberculosis (Mtb) transmission, a challenge exacerbated by our poor understanding of the events enabling successful transfer of infectious bacilli between hosts. To address this problem, we developed the Respiratory Aerosol Sampling Chamber (RASC), a personal clean-room equipped with high-efficiency filtration and sampling technologies that allow biosafe capture and isolation of… 

Sensitivity optimisation of tuberculosis bioaerosol sampling

Technical improvements in particle collection together with sensitive detection enable rapid quantitation of viable Mtb in bioaerosols of sputum positive TB cases and suggests the potential utility of bio aerosol measurement for rapid intervention in other airborne infectious diseases.

Bioaerosol sampling of patients with suspected pulmonary tuberculosis: a study protocol

A sensitive air sampling protocol is proposed to be used to investigate the prevalence of Mtb -containing bioaerosols in both sputum-positive and spUTum-negative TB suspects, at the same time evaluating the potential to identify unrecognized transmitters of TB.

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