Capture Hi-C reveals novel candidate genes and complex long-range interactions with related autoimmune risk loci.

Abstract

Genome-wide association studies have been tremendously successful in identifying genetic variants associated with complex diseases. The majority of association signals are intergenic and evidence is accumulating that a high proportion of signals lie in enhancer regions. We use Capture Hi-C to investigate, for the first time, the interactions between… (More)
DOI: 10.1038/ncomms10069

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@article{Martin2015CaptureHR, title={Capture Hi-C reveals novel candidate genes and complex long-range interactions with related autoimmune risk loci.}, author={Paul Martin and Amanda McGovern and Gisela Orozco and Kate Duffus and Annie Yarwood and Stefan Schoenfelder and Nicholas Cooper and Anne Barton and Chris Wallace and Peter Fraser and Jane Worthington and Stephen Eyre}, journal={Nature communications}, year={2015}, volume={6}, pages={10069} }