Capture, release and culture of circulating tumor cells from pancreatic cancer patients using an enhanced mixing chip.

@article{Sheng2014CaptureRA,
  title={Capture, release and culture of circulating tumor cells from pancreatic cancer patients using an enhanced mixing chip.},
  author={Weian Sheng and Olorunseun O. Ogunwobi and Tao Chen and Jinling Zhang and Thomas J. George and Chen Liu and Ziqi Fan},
  journal={Lab on a chip},
  year={2014},
  volume={14 1},
  pages={89-98}
}
Circulating tumor cells (CTCs) from peripheral blood hold important information for cancer diagnosis and disease monitoring. Analysis of this "liquid biopsy" holds the promise to usher in a new era of personalized therapeutic treatments and real-time monitoring for cancer patients. But the extreme rarity of CTCs in blood makes their isolation and characterization technologically challenging. This paper reports the development of a geometrically enhanced mixing (GEM) chip for high-efficiency and… CONTINUE READING
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