Captopril reverses the reduced vasodilator response to bradykinin in hypertensive pregnant rats.

@article{Resende2004CaptoprilRT,
  title={Captopril reverses the reduced vasodilator response to bradykinin in hypertensive pregnant rats.},
  author={Angela Castro Resende and Adriana M L Pimentel and Roberto Soares de Moura},
  journal={Clinical and experimental pharmacology & physiology},
  year={2004},
  volume={31 11},
  pages={756-61}
}
1. Pregnancy in rats is characterized by a reduction in arterial pressure that is associated with a decreased response to vasoconstrictors. However, the responses to vasodilators in isolated vessels remain controversial and are not well established in hypertensive pregnant rats. 2. In the present study, we investigated the effect of pregnancy on the bradykinin (BK)-induced vasodilator responses of the isolated mesenteric arterial bed (MAB) from Wistar normotensive and spontaneously hypertensive… CONTINUE READING

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