Captopril reduces deposition of collagen in lamina propria and muscular layers of the bladder and ureter in neonatal dogs with partial urethral obstruction.

@article{Shirazi2008CaptoprilRD,
  title={Captopril reduces deposition of collagen in lamina propria and muscular layers of the bladder and ureter in neonatal dogs with partial urethral obstruction.},
  author={Mehdi Ramezan Shirazi and Ali Noorafshan and Mohammad Arabzadeh Bahri and Abbas Hassanpoor},
  journal={Scandinavian journal of urology and nephrology},
  year={2008},
  volume={42 4},
  pages={
          324-9
        }
}
OBJECTIVE It has been recognized that most boys with posterior urethral valve ablation have varying degrees of ureteral dilation and abnormal bladder function. It has been shown that deposition of collagen in the bladder layers increases the intravesical pressure that is transmitted to the pelvicalyceal system. The purpose of this study was to evaluate, using stereological methods, the effect of captopril on prevention of collagen formation in different layers of the ureter and bladder under… CONTINUE READING
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