Captopril inhibits maturation of dendritic cells and maintains their tolerogenic property in atherosclerotic rats.

@article{Li2015CaptoprilIM,
  title={Captopril inhibits maturation of dendritic cells and maintains their tolerogenic property in atherosclerotic rats.},
  author={H. Li and Q. Zhang and L. Chen and C. Yin and P. Chen and Jie Tang and R. Rong and T. Li and Li-qun Hu},
  journal={International immunopharmacology},
  year={2015},
  volume={28 1},
  pages={
          715-23
        }
}
Atherosclerosis (AS) is a systemic disease of the immune system featuring hyperactive dendritic cells (DCs) in atherosclerotic plaques and organs. Captopril, a representative medicine of angiotensin-converting enzyme inhibitors, has been demonstrated to be effective in treating AS. However, captopril's anti-atherosclerotic mechanism is still poorly understood. Therefore, this study was primarily performed to investigate the effects of captopril on the function of DCs in vivo. AS in rats was… Expand
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References

SHOWING 1-10 OF 50 REFERENCES
Captopril suppresses inflammation in endotoxin-induced uveitis in rats.
  • 36
  • PDF
T cell-based therapies for atherosclerosis.
  • 24
...
1
2
3
4
5
...