Captopril inhibits maturation of dendritic cells and maintains their tolerogenic property in atherosclerotic rats.

@article{Li2015CaptoprilIM,
  title={Captopril inhibits maturation of dendritic cells and maintains their tolerogenic property in atherosclerotic rats.},
  author={Hong-qi Li and Qi Zhang and Li Chen and Chang-sen Yin and Ping Chen and Jie Tang and Rong Rong and Ting-Ting Li and Li-qun Hu},
  journal={International immunopharmacology},
  year={2015},
  volume={28 1},
  pages={
          715-23
        }
}
  • Hong-qi Li, Qi Zhang, +6 authors Li-qun Hu
  • Published in
    International…
    2015
  • Medicine
  • Atherosclerosis (AS) is a systemic disease of the immune system featuring hyperactive dendritic cells (DCs) in atherosclerotic plaques and organs. Captopril, a representative medicine of angiotensin-converting enzyme inhibitors, has been demonstrated to be effective in treating AS. However, captopril's anti-atherosclerotic mechanism is still poorly understood. Therefore, this study was primarily performed to investigate the effects of captopril on the function of DCs in vivo. AS in rats was… CONTINUE READING

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