Captopril-induced pemphigus vegetans with Charcot-Leyden crystals.

  title={Captopril-induced pemphigus vegetans with Charcot-Leyden crystals.},
  author={Giselle Martins Pinto and P Lamar{\~a}o and Tom Vale},
  journal={Journal of the American Academy of Dermatology},
  volume={27 2 Pt 2},
A 78-year-old woman developed intertriginous vegetating plaques, mouth ulcers, and a cerebriform tongue after 11 months of captopril therapy. Findings of clinical, histologic, and immunofluorescence testing were consistent with a diagnosis of pemphigus vegetans. In addition, Charcot-Leyden crystals were observed within some of the intraepidermal, eosinophilic abscess cavities, which were bordered by granular cells undergoing keratinization. The skin lesions cleared rapidly after discontinuation… CONTINUE READING