Captopril as a Potential Inhibitor of Lung Tumor Growth and Metastasis

@article{Attoub2008CaptoprilAA,
  title={Captopril as a Potential Inhibitor of Lung Tumor Growth and Metastasis},
  author={Samir Attoub and A M Gaben and Suhail Al-Salam and Mahmood Ahmed Al Sultan and Anne John and Michael Gary Nicholls and J{\'a}n Mester and Georg A. Petroianu},
  journal={Annals of the New York Academy of Sciences},
  year={2008},
  volume={1138}
}
Lung cancer is the most common form of cancer in the world, and 90% of patients die from their disease. The angiotensin converting enzyme (ACE) inhibitors are used widely as antihypertensive agents, and it has been suggested that they decrease the risk of some cancers, although available data are conflicting. Accordingly, we investigated the anticancer activity of the ACE inhibitor, captopril, in athymic mice injected with highly tumorigenic LNM35 human lung cells as xenografts. Using this… 

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