Captopril: a new treatment for rheumatoid arthritis?

@article{Martn1984CaptoprilAN,
  title={Captopril: a new treatment for rheumatoid arthritis?},
  author={Mar{\'i}a Rodr{\'i}guez Mart{\'i}n and K. E. Surrall and Frank Mckenna and J. Scott Dixon and Howard A. Bird and Virginia F. Wright},
  journal={Lancet},
  year={1984},
  volume={1 8390},
  pages={1325-8}
}
Captopril, an inhibitor of angiotensin converting enzyme, is prescribed for hypertension. Its molecular structure shares features with D-penicillamine, in that both agents contain a thiol group. In addition, captopril has immunosuppressant activity. Captopril was therefore considered a potential slow-acting drug for treating rheumatoid arthritis. In an open study 15 patients with active arthritis were treated with captopril and followed for 48 weeks. Two-thirds of the patients reported improved… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 46 extracted citations

Similar Papers

Loading similar papers…