Capsinoids and related food ingredients activating brown fat thermogenesis and reducing body fat in humans

@article{Saito2013CapsinoidsAR,
  title={Capsinoids and related food ingredients activating brown fat thermogenesis and reducing body fat in humans},
  author={Masayuki Saito and Takeshi Yoneshiro},
  journal={Current Opinion in Lipidology},
  year={2013},
  volume={24},
  pages={71–77}
}
Purpose of review Capsaicin and its nonpungent analog (capsinoids) are known to be food ingredients that increase energy expenditure and decrease body fat. This article reviews the role of brown adipose tissue (BAT) for the thermogenic effect of these compounds in humans and proposes the possibility of some other antiobesity food ingredients. Recent findings A single oral ingestion of capsinoids increases energy expenditure in human individuals with metabolically active BAT, but not those… 
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TLDR
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TLDR
Cinsinoid ingestion increases EE through the activation of BAT in humans through the impact of capsinoids on whole-body energy expenditure and skin temperature.
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TLDR
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TLDR
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TLDR
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TLDR
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TLDR
Treatment with 6 mg/d capsinoids orally appeared to be safe and was associated with abdominal fat loss and 2 common genetic variants that may be predictors of therapeutic response were identified.
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TLDR
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TLDR
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TLDR
Capsinoids provided in four doses did not affect metabolic rate and fuel partitioning in human subjects when measured 2 h after exposure, and longer exposure and higher capsinoids doses may be required to cause meaningful acute effects on energy metabolism.
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