Capsinoids activate brown adipose tissue (BAT) with increased energy expenditure associated with subthreshold 18-fluorine fluorodeoxyglucose uptake in BAT-positive humans confirmed by positron emission tomography scan.

@article{Sun2018CapsinoidsAB,
  title={Capsinoids activate brown adipose tissue (BAT) with increased energy expenditure associated with subthreshold 18-fluorine fluorodeoxyglucose uptake in BAT-positive humans confirmed by positron emission tomography scan.},
  author={Lijuan Sun and Stefan Gerardus Camps and Hui Jen Goh and Priya Govindharajulu and Joshua J. D. Schaefferkoetter and David W. Townsend and Sanjay Kumar Verma and Sendhil S. Velan and Lei Sun and Siu Kwan Sze and Su Chi Lim and B O Boehm and Christiani Jeyakumar Henry and Melvin Khee-Shing Leow},
  journal={The American journal of clinical nutrition},
  year={2018},
  volume={107 1},
  pages={62-70}
}
Background Capsinoids are reported to increase energy expenditure (EE) via brown adipose tissue (BAT) stimulation. However, imaging of BAT activation by capsinoids remains limited. Because BAT activation is a potential therapeutic strategy for obesity and related metabolic disorders, we sought to prove that capsinoid-induced BAT activation can be visualized by 18-fluorine fluorodeoxyglucose (18F-FDG) positron emission tomography (PET). Objective We compared capsinoids and cold exposure on BAT… CONTINUE READING