Capsid-Dependent Host Factors in HIV-1 Infection.

@article{Yamashita2017CapsidDependentHF,
  title={Capsid-Dependent Host Factors in HIV-1 Infection.},
  author={Masahiro Yamashita and Alan N. Engelman},
  journal={Trends in microbiology},
  year={2017},
  volume={25 9},
  pages={
          741-755
        }
}
After invasion of a susceptible target cell, HIV-1 completes the early phase of its life cycle upon integration of reverse-transcribed viral DNA into host chromatin. The viral capsid, a conical shell encasing the viral ribonucleoprotein complex, along with its constitutive capsid protein, plays essential roles at virtually every step in the early phase of the viral life cycle. Recent work has begun to reveal how the viral capsid interacts with specific cellular proteins to promote these… CONTINUE READING
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