Capsaicin treatment in adult Wistar-Kyoto and spontaneously hypertensive rats: effects on substance P contents of peripheral and central nervous system tissues.

@article{Virus1982CapsaicinTI,
  title={Capsaicin treatment in adult Wistar-Kyoto and spontaneously hypertensive rats: effects on substance P contents of peripheral and central nervous system tissues.},
  author={R. M. Virus and D. Mcmanus and G. F. Gebhart},
  journal={European journal of pharmacology},
  year={1982},
  volume={81 1},
  pages={
          67-73
        }
}
  • R. M. Virus, D. Mcmanus, G. F. Gebhart
  • Published 1982
  • Chemistry, Medicine
  • European journal of pharmacology
  • The effects of s.c. capsaicin treatment on the contents of immunoreactive substance P (ISP) in several peripheral and central nervous system tissues were examined in normotensive Wistar-Kyoto (WKY) and spontaneously hypertensive (SHR) rats. Significant differences between vehicle-treated subjects of the WKY and SHR strains were observed in the ISP contents of both superior cervical and celiac sympathetic ganglia. Capsaicin pretreatment significantly reduced the ISP contents of both sympathetic… CONTINUE READING
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