Capsaicin-sensitive nerves and the cutaneous allergy reaction in man. Possible involvement of sensory neuropeptides in the flare reaction.

@article{Lundblad1987CapsaicinsensitiveNA,
  title={Capsaicin-sensitive nerves and the cutaneous allergy reaction in man. Possible involvement of sensory neuropeptides in the flare reaction.},
  author={Lars Lundblad and Jan M. Lundberg and Anders Angg{\aa}rd and Olle Zetterstr{\"o}m},
  journal={Allergy},
  year={1987},
  volume={42 1},
  pages={20-5}
}
The effects of local capsaicin pretreatment on the cutaneous triple response reaction induced by allergen exposure or anti-IgE were studied in man. Acute exposure of the human skin to capsaicin caused a burning sensation and a clearcut flare reaction but no wheal response. Upon repeated administration these local reactions to capsaicin disappeared. The flare component and the subjective itching sensation of the cutaneous allergy reaction to rat antigen in sensitized persons or anti-IgE in non… CONTINUE READING