Capsaicin-sensitive afferents in the rat urinary bladder activate a spinal sympathetic cardiovascular reflex

@article{Giuliani1988CapsaicinsensitiveAI,
  title={Capsaicin-sensitive afferents in the rat urinary bladder activate a spinal sympathetic cardiovascular reflex},
  author={Sandro Giuliani and Carlo A. Maggi and Alberto Meli},
  journal={Naunyn-Schmiedeberg's Archives of Pharmacology},
  year={1988},
  volume={338},
  pages={411-416}
}
In urethane-anesthetized rats with an intact spinal cord, application of capsaicin on the outer surface of the urinary bladder produced a transient bradycardia, hypotension and negative cardiac inotropism which were neither prevented by i. v. atropine (0.5 mg/kg) nor by cervical vagotomy. In acute spinal rats (C2-C3) application of capsaicin (0.2 and 2 pg in 25 pl) on the urinary bladder induced a transient hypertension, tachycardia and positive cardiac inotropism. A second application (30 min… CONTINUE READING
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The contribution of capsaicinsensitive sensory nerves to xyleneinduced visceral pain in conscious , freely moving rats

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